Expanding the Cannabis Delivery
System Options

The most common methods to deliver cannabinoids to the endocannabinoid system are smoking the flowers of the plant and the extraction of plant material into oil – for further processing for the creation of tinctures, topicals, edibles and vape liquids. While relatively simple to execute,
each of these methods are considerably limited in their usefulness.

Smoking cannabis is common for recreational users largely because it’s easy to do, although dosing not accurate (the level of cannabinoid ingested while smoking can vary from plant to plant). While this is ok for recreational users, the lack of consistency is an important consideration for medical patients. Further, smoking can irritate the lungs, cause allergies, and accelerate the symptoms associated with chronic bronchitis, making it incompatible with a number of conditions. Research indicates that these factors result in up to 30% of patients licensed to use cannabis
for medicinal purposes not want to smoke and therefore not utilize their license.

Vaping has less impact on the respiratory system, however, common additives to vape oils, such as propylene glycol, used to thin the oil for use in vape pens and
cartridges, can result in exposure to harmful carcinogenic compounds when heated and inhaled.
Oral formulations such as edibles, tinctures and supplements, allow for more accurate dosing, however as cannabinoids are lipophilic – i.e. oil-based – they tend to be poorly absorbed when ingested due to the aqueous environment of gastrointestinal tract, resulting in lower bioavailability.

Topicals, such as transdermal patches, balms, creams and serums, are useful in targeting specific areas, however the skin is not especially permeable, particularly for molecules the size of unprocessed cannabinoids.

These limitations result in material amounts of cannabinoids not being absorbed by the body, meaning users must consume greater amounts in order to attain the desired dosage, making these delivery mechanisms ineffective and more expensive

than necessary. More significantly, they restrict the range of applications and indications for which cannabis becomes an effective treatment.

CannaPowder’s nanometric powders eliminate many, if not all of these limitations and provide many benefits to existing manufacturers of cannabis-related products, as well as providing opportunities for producers previously unwilling to use cannabinoids in their products.